ANVAR / OSEO-BPI
This STEM ALPHA development was supported by ANVAR (Agence Nationale de la Valorisation pour la Recherche) / Oseo-BPI, Rhône-Alpes, France. Project N° A0303118V (Head of project : Daniel LICARI)
STEM ALPHA design and development
STEM ALPHA has designed and developed 26 prototypes, tested between 2001 and 2003
Objectives :
– to improve the quality of the delivered grafts – to reduce the loss of cornea by excessive endothelial cells loss at the end of conservation
– to improve health safety (animal component free media)
Results
The results obtained after use by cornea banks and patients follow-up confirmed the pre-clinical expected results.
Patent_2019
METHOD AND DEVICE FOR PREPARING AN IMPLANT OBTAINED FROM A CULTURE OF STEM CELLS
……….Extract
“A suitable liquid can be used beforehand to fill the volume above the gel layer in the tubular element 31 of the support 30, in particular in order to keep the gel layer in a humid environment. This liquid can be, for example, a liquid used for the transport of human corneas such as STEM ALPHA. 1® marketed by the company STEM ALPHA. Thus, the handling device 10 associated with the transport cover makes it possible to transport the implant to the site where it is to be transplanted and to keep it cold (at a temperature below 10° C.) until the time of transplantation.”
Patent History
Publication number: 20210023273
Type: Application
Filed: Mar 12, 2019
Inventors: Karim BEN M’BAREK (CRETEIL), Walter HABELER (PARIS), Christelle MONVILLE (CHAMPIGNY SUR MARNE)
Application Number: 16/980,120
Classifications International Classification: A61L 27/38 (20060101); A61L 27/52 (20060101); C12M 3/00 (20060101); C12M 1/12 (20060101); C12M 1/00 (20060101); C12N 5/079 (20060101); C12N 5/0735 (20060101); C12N 5/071 (20060101);